Beyond the two leads, Sam & Cat featured a tight supporting cast anchored by veteran performers and promising child actors. Cameron Ocasio portrayed Dice Corleone, the neighborhood young hustler and tenant manager who supplied comic relief with fast-talking schemes. Following the show's abrupt ending, Ocasio appeared in several small independent features before shifting his focus away from full-time auditioning. Holding a black belt in martial arts, Ocasio pivoted toward athletic coaching, working as a martial arts instructor and mentor in New York, occasionally engaging with fans on social media to reminisce about the Nickelodeon era.
Maree Cheatham brought decades of legitimate soap-opera royalty to the set as Cat's eccentric grandmother, Nona Valentine. Having originated the role of Marie Horton on Days of Our Lives in 1965 and starred in hundreds of episodes of General Hospital, Cheatham treated her time on the sitcom as a fun, breezy detour. After 2014, she immediately transitioned back into prestige television and daytime dramas, securing recurring roles in FX's critically acclaimed comedy Baskets, Young Sheldon, and returns to daytime serials. Her sixty-year career remains a model of steady, professional longevity in an industry notorious for volatility.